Expiration date: 01/2025
Structure and Composition:
Tablets. One tablet contains active substance:
doxazosin mesylate 2.44 mg (In terms of doxazosin - 2 mg)
Excipients: potato starch lactose (milk sugar) MCC povidone colloidal silicon dioxide (Aerosil), sodium lauryl sulfate (sodium dodecyl sulphate), magnesium stearate
in the package strip cellular PVC film and aluminum foil printed patent 10 items. in a stack of cardboard 3 or 30 packs.
Tablets. One tablet contains active substance:
doxazosin mesylate 4.88 mg (In terms of doxazosin - 4 mg)
Excipients: lactose, starch potato (milk sugar), povidone (Kollidon 25), crospovidone (Kollidon CL) Magnesium stearate
in the package strip cellular PVC film and aluminum foil printed patent 10 items. in a stack of cardboard 3 packaging.
Dosage and administration:
Inside, regardless of meals, without chewing and drinking plenty of water, 1 time a day (morning or evening).
To ensure the below dosage regimen Artezin possible to use the drug in the dosage form: tablets of 1 mg, 2 mg or 4 mg.
When hypertension the initial dose is 1 mg / day, at bedtime.
After the first dose the patient must stay in bed for 6-8 hours.
This is required in connection with the development of the "first dose phenomenon", especially pronounced on the background of the previous diuretics.
When insufficient therapeutic effect daily dose can be increased to 2 mg every 1-2 weeks. Subsequently, every 1-2 weeks the dose may be increased to 2 mg. The vast majority of patients, the optimal therapeutic effect is achieved at a dose of 8 mg / day.
The maximum dose - 16 mg / day - can not be exceeded.
After reaching a stable dose of a therapeutic effect is usually somewhat lower (average therapeutic dose of the drug in Artezin maintenance therapy is usually 2-4 mg / day).
When treating BPH patients the initial dose - 1 mg / day to minimize the possibility of orthostatic hypotension and / or syncope. If necessary, depending on the performance and availability of urodynamics BPH symptoms increase the dose (1-2 week intervals) to 2.4 mg / day.
The maximum permissible dose is equal to 8 mg / day. The recommended maintenance dose - 2-4 mg / day.
The drug is used long Artezin. Duration of treatment is determined by the attending physician.
