Expiration date: 05/2025

Release form and composition: 

Tablets, film-coated from yellow-brown to light brown with a pinkish tinge, biconvex, oblong.

1 tablet contains:

retinol acetate (Vit. A) 1650 IU (567.5 g)

apha-tocopherol acetate (Vit. E) 20 mg

ergocalciferol (Vit. D2) 250 IU (6.25 µg)

ascorbic acid (Vit. C) 100 mg

thiamine hydrochloride (Vit. B1) 2 mg

Riboflavin (Vit. B2) 2 mg

calcium Pantothenate (Vit. B5) 10 mg

pyridoxine hydrochloride (Vit. B6) 5 mg

folic acid (Vit. Bc) 400 mcg

cyanocobalamin (Vit. B12) 5 mcg

nicotinamide (Vit. PP) 20 mg

calcium (in the form of phosphate dihydrate) 25 mg

magnesium (carbonate) 25 mg

phosphorus (calcium phosphate dihydrate) 19 mg

iron (in the form of the sulfate hydrate) 10 mg

copper (sulfate pentahydrate) 2 mg

zinc (sulfate) 10 mg

manganese (in the form of the sulfate hydrate) 2.5 mg

Excipients: silica colloidal anhydrous, talc, potato starch, citric acid, povidone, calcium stearate, stearic acid, gelatin, sucrose, hydroxypropyl cellulose, polyethylene oxide-4000, titanium dioxide, dye acid red dye (E104), tropeolin O.

30 PCs banks polymer (1) - packs of cardboard.

60 PCs banks polymer (1) - packs of cardboard.

Pharmacological action:

Combined multivitamin preparation with micro - and macroelements, which is due to the effects of its constituent components.

The compatibility of components in a single tablet has special technology of production of vitamin-mineral complexes.

apha tocopherol acetate (vitamin E) has antioxidant properties, maintains the stability of the red blood cells, prevents hemolysis has a positive effect on gonadal function, nervous and muscular tissue. A deficiency of vitamin E in early pregnancy can cause miscarriage.

Retinol acetate (vitamin a) plays an important role in redox processes involved in the synthesis of mucopolysaccharides, proteins, and lipids. Promotes normal spermato - and oogenesis, development of the placenta, growth, normal development and differentiation of embryonic tissues, including epithelial structures and bone. Participates in forming of optic pigments, necessary for normal twilight and color vision, maintains the integrity of epithelial tissues, regulates bone growth.

Thiamine hydrochloride (vitamin B1) as coenzyme is involved in carbohydrate metabolism, functioning of the nervous system.

Riboflavin (vitamin B2) is a vital catalyst in cellular respiration and visual perception.

Pyridoxine hydrochloride (vitamin B6) as a coenzyme involved in protein metabolism and synthesis of neurotransmitters. During pregnancy required women who took oral contraceptives previously, depleting reserves of pyridoxine in the body.

Cyanocobalamin (vitamin B12) is involved in the synthesis of nucleotides is an important factor for normal growth, hematopoiesis and development of epithelial cells is essential for the metabolism of folic acid and myelin synthesis.

Nicotinamide (vitamin PP) is involved in tissue respiration, lipid and carbohydrate metabolism.

Ascorbic acid (vitamin C) provides the synthesis of collagen, participates in the formation and maintenance of the structure and function of cartilage, bones and teeth, affects the formation of hemoglobin, erythrocyte maturation. Vitamin C increases the body's resistance to infections, reduces inflammatory reactions.

Calcium Pantothenate (vitamin B5) as an integral part of coenzyme a plays an important role in the acetylation and oxidation promotes regeneration of the epithelium and endothelium.

Folic acid (vitamin BC) participates in the synthesis of amino acids, nucleotides, nucleic acids required for normal erythropoiesis. In the early stages of pregnancy reduces risk of fetal neural tube defects and the risk of malformations of the maxillofacial region.

Iron is involved in erythropoiesis, hemoglobin provides oxygen transport in tissue prevents the development of anemia in pregnant women, especially in II and III trimestrah pregnancy.

Copper prevents anemia and oxygen starvation of organs and tissues, helps prevent osteoporosis, strengthens the walls of blood vessels.

Manganese has anti-inflammatory properties, prevents the development of osteoarthritis.

Zinc is essential for normal formation of the fetal skeleton and tissue regeneration, participates in the formation of certain hormones, including insulin reduces the risk of several fetal anomalies. In combination with retinol promotes the formation of normal twilight and color vision.

Magnesium normalizes blood pressure and has a sedative action, reduces the likelihood of developing pre-eclampsia, spontaneous abortion, premature birth.

Calcium is involved in bone formation, promotes normal blood clotting, participates in processes of transmission of nerve impulses, contractions of skeletal and smooth muscles, regulation of cardiac activity.

Phosphorus strengthens the bones and teeth, enhances mineralization, is part of ATP – the energy source of cells.

Pharmacokinetics:

The effect of the drug is the combined effect of its components, is a kinetic observation is not possible all components can be traced using markers or research.

Indications:

Prevention and treatment of hypovitaminosis and mineral deficiencies:

• in preparation for pregnancy
  
• during pregnancy and breastfeeding.
  

Dosing regimen:

The drug is recommended to take 1 tab. 1 time/day during or after Breakfast, drinking plenty of fluids. Course duration is determined individually.

Side effects:

Possible: allergic reactions to components of the drug.

Contraindications:

• hypervitaminosis A
  
• high content of calcium and iron in the body
  
• urolithiasis
  
• pernicious vitamin B12 deficiency anemia
  
• children's age
  
• hypersensitivity to the drug.
  

Pregnancy and lactation:

The drug is used during pregnancy and lactation on the testimony at the recommended doses.

Special instructions:

Not recommended to take this drug in conjunction with other multivitamin preparations in order to avoid overdose.

In appointing the drug should be considered that a daily dose of retinol acetate during pregnancy should not exceed 5,000 IU.

Possible staining of urine in an intense yellow color, which is not dangerous, because due to the presence of Riboflavin in the composition of the drug.

Overdose:

The patient should be informed that in case of overdose, contact the doctor.

Treatment: temporary cessation of the drug, gastric lavage, administration of activated charcoal if necessary, symptomatic therapy.

Drug interactions:

The drug contains iron and calcium, so in a joint application of antibiotics of tetracycline and fluoroquinolones is a slowdown in the last absorption from the gastrointestinal tract.

Ascorbic acid enhances the pharmacological action and side effects of antimicrobial agents from the group of sulfonamides (including increases the risk of christallurii).

While the use of antacids, which contain aluminum, calcium, magnesium, and cholestyramine decreases the absorption of iron.

When used together with thiazide diuretics increases risk of hypercalcemia.

Terms and conditions of storage:

The drug should be stored in a dry, dark, inaccessible to children place at temperature not exceeding 25°C. shelf Life - 3 years.