Expiration date: 09/2025
Structure and Composition:
1 tablet, film-coated, contains 10, 25 or 50 mg thioridazine hydrochloride in blisters of 10 pcs., In a cardboard bundle 10 packages.
Pharmachologic effect:
Blocks alpha-adrenergic, dopaminergic, m-cholinergic receptors.
Indications:
Schizophrenia, manic-depressive psychosis, neurosis, fear, excitement, stress, obsessive-compulsive disorder, tic, psychomotor agitation, withdrawal syndrome.
Contraindications:
Hypersensitivity, coma, depression, severe central nervous system diseases, cardiovascular system, liver.
Side effect:
Extrapyramidal disorders pseudoparkinsonism, drowsiness, confusion, restlessness, excessive motor excitability, headache, dry mouth, nausea, vomiting, diarrhea, jaundice, paresis of accommodation, dysmenorrhea, abnormal ejaculation, swelling, nipple breast, allergic reactions.
Drug Interactions:
Inside, an exacerbation of schizophrenia in adult hospitalized patients: Adults with outpatient treatment in mild cases - 10-25 mg 2-4 times a day, with stationary and in more severe cases - 300-600 mg / day in divided doses. Children 4-7 years - 10-20 mg / day, splitting the dose by 2-3 hours, 8-14 years - 20-30, 15-18 - 30-50 mg / day. The treatment ends with a gradual reduction in dosage.
Dosage and administration:
Inside, adults with acute exacerbation of schizophrenia in hospitalized patients: 100-600 mg / day - up to a maximum dose of 800 mg / day in chronic schizophrenia hospitalized patients - 100-600 mg / day, outpatients - 50-300 mg / day.
The syndrome of anxiety and depression in psychiatric practice patients with agitated depression - 25-200 mg / day. In general medical practice as a sedative and anxiolytic - 10-75 mg / day.
Older patients as a neuroleptic / antipsychotic - 25-200 mg / day, anxiolytic / sedative - 10-75 mg / day.
Children older than 2 years in the treatment of severe mental and emotional disorders: as neuroleptic dose of 1-3 mg / kg / day, as anxiolytic / sedative - dose of 0.5-2 mg / kg / day.
When treating pronounced behavioral disorders in mentally retarded adults and in patients with deficiency of symptoms: 100-600 mg / day, the maximum dose - 800 mg / day. To reduce the severity of mental disorders with alcohol withdrawal syndrome: 100-200 mg / day.
Patients with low body weight, impaired renal function and / or liver function, elderly patients and children need to decrease doses. The treatment ends with a gradual reduction in dose.
