Expiration date: 08/2025
The composition and form of issue:
Lozenges. 1 tablet contains:
moskomarhitectura antibodies to protein S-100 affinity purified (introduced in the form of a water-alcohol mixture of the active form of the active substance) 0, 003 g
other ingredients: microcrystalline cellulose magnesium stearate lactose
1 the Active form of the active substance, the active form content of not more than 10-1991 ng/g of active substance
in a cell contour packing 20 PCs. in cardboard pack 1, 2 or 5 packs.
Drops for reception inside 100 g
moskomarhitectura antibodies to protein S-100 affinity purified (introduced in the form of a water-alcohol mixture of the active form of the active substance) 1 g
excipients: ethyl alcohol (ethanol) 95% (vol./vol.) purified water
1 the Active form of the active substance, the active form content of not more than 10-1991 ng/g of active substance
in bottles of dark glass by 25 ml complete with stopper-dropper in 1 box set.
Description pharmaceutical form:
Tablets from white to almost white color, valium forms, with valium and chamfer. On the flat side with the mark affixed MATERIA MEDICA, on the other flat side of PROPROTEN 100.
Drops: colorless, transparent liquid with a characteristic alcohol odor.
Description pharmacological action:
Modifies the functional activity of protein S-100, those in the brain pairing information and metabolic processes. Sensititive the neuronal membrane, modulates the synaptic plasticity of neurons. Has modifying effect on the functional state of brain structures involved in the formation of alcohol dependence: hypothalamus, hippocampus, etc.
When alcohol addiction has a normalizing effect on the system of positive emotional reinforcement, which leads to a decrease in the frequency of self-stimulation of lateral hypothalamus. Reduces burst activity of the hippocampal neurons reduces the number of circulating immuno complexes in the peripheral blood that correlated with a decrease in consumption of ethanol. Enhances the braking effect of GABA in the CNS. It was established experimentally that the drug restores the neurotransmitter balance and the conditioned-reflex activity. Increases resistance to cerebral hypoxia and toxic influences.
Indications:
Shows antialcoholic effect, reducing the craving for alcohol and reducing the likelihood of relapse.
Monotherapy alcohol withdrawal syndrome mild and moderate severity. Facilitates as psychopathological disorders (anxiety, mental tension, insomnia, irritability, anxiety, depressed mood, intense attraction to alcohol) and somatic vegetative disorders (weakness, sweating, headache, tremor, tachycardia, digestive disorders) alcohol withdrawal syndrome.
Contraindications:
Increased individual sensitivity to product components, pregnancy and lactation.
Side effects:
Possible reactions of individual hypersensitivity to the drug components.
Drug interactions:
No incompatibilities with other drugs to date not been identified.
Method of application and dose:
Inside, 1 tab. (hold in mouth until dissolved) or 10 drops in 1 tbsp. spoon of water, not at mealtimes.
The hangover in the first 2 h — 1 table. or 10 drops every 30 min in the subsequent 8-10 h — 1 table. or 10 drops per hour. In the event of receiving resume sleep after awakening. In the future, when improvement in the 1 table. or 10 drops every 2-3 hours (4-6 meals per day) for 2-3 days.
When weighting of the symptoms of alcohol withdrawal to therapy you want to join BOS, is traditionally used in detoxification.
Prevention of relapse on the table 1-2. a day or 10 drops 1-2 times a day for 2-3 months after a random alcohol take an additional 10 drops of the drug 2 times a day and at night.
Overdose:
In case of accidental overdose dyspepsia caused by members of the drug fillers.
Special instructions:
Part of the tablets includes lactose, and therefore it is not recommended to appoint patients with congenital galactosemia, syndrome of malabsorption of glucose or congenital lactase deficiency.
