Expiration date: 02/2025
The composition and form of issue:
Tablets. 1 tablet contains:
magnesium orotate dihydrate 500 mg
excipients: carmellose sodium starch maize silica colloidal anhydrous lactose monohydrate magnesium stearate sodium cyclamate, povidone K30 talc MCC
blistere in 10 PCs., in box 2, or 5 blisters.
Description pharmaceutical form:
White pill scored on one side.
Description pharmacological action:
Magnesium is an essential macromineral. Necessary to provide many of the energy processes involved in the metabolism of proteins, fats, carbohydrates, and nucleic acids. Magnesium takes part in the process neuromuscular stimulation, inhibiting neuromuscular transmission. Of special interest is the magnesium as a natural physiological antagonist of calcium. Magnesium controls the normal functioning of the cells of the myocardium, involved in the regulation of myocardial contractile function. In stressful situations, you receive an increased amount of free ionized magnesium, in connection with which extra magnesium helps increase resistance to stress.
Part Magnerot includes orotic acid, which promotes cell growth, is involved in the process of metabolism. In addition, orotic acid is necessary for fixation of magnesium ATP in the cell and the effects of his actions.
Indications:
- complex treatment and prevention of myocardial infarction, chronic heart failure, arrhythmia caused by magnesium deficiency
- spastic conditions (including vasospasm), atherosclerosis, hyperlipidemia — complex treatment and prevention
- treatment and prevention of calf muscle cramps.
Contraindications:
- hypersensitivity to the drug
- the human kidney stone disease
- cirrhosis of the liver with ascites.
Application of pregnancy and breast-feeding:
During pregnancy and lactation (breastfeeding) is possible with care and according to the testimony, because at that time the need for magnesium increases. If its content is not balanced, it can lead to serious complications, including miscarriage.
Side effects:
Gastrointestinal: unstable stool and diarrhea (with high doses), which usually disappear at lower doses of the drug.
Allergic reactions: allergic dermatitis.
Method of application and dose:
Inside. Table 2. 3 times a day for 7 days, then 1 tab. 2-3 times a day, every day. Course duration — not less than 4-6 weeks. Repeated course is possible after consulting a doctor. For night leg cramps it is recommended to take 2-3 table. in the evenings.
Overdose:
Perhaps the increasing incidence described side effects.
Special instructions:
Magnerot can be applied for a long time. Note that the deficiency of magnesium in the body can cause diseases of the gastrointestinal tract, consumption of foods with reduced content of magnesium, chronic alcoholism (due to the reduction of resorption of magnesium in the renal tubules and enhance the excretion of magnesium from the body), certain medications (oral contraceptives, diuretics, muscle relaxants, glucocorticoids, insulin), conditions requiring increased intake of magnesium (lack of exercise, stress, pregnancy).
