Expiration date: 04/2025

Structure and Composition:

Vaginal Suppositories. 1 suppositorie contains estriol 0.5 mg

Excipients: cetomacrogol glitserolmonoritsinoleat tallow

in blister 5 pieces. In the paper cartons 2 blisters.

Testimony:

Diseases caused by deficient estrogen in the body: involution (atrophy) of the vagina and vulva, accompanied by itching, burning and vaginal dryness, pain during sexual intercourse (dyspareunia), coleitis, vulvitis, cervicitis, leucorrhea, narrowing of the vagina, sores in the vagina and on the cervix uterus, resulting from pressure or tension, concomitant therapy for vaginal infections and involuntary urination (incontinence), atrophy of the lower urinary tract (urethrocystitis), pre- and post-operative treatment for vaginal operations, diagnosis under uncertain outcome of vaginal smear, if there is changes in the cellular composition of the picture on the background of signs of involution.

Contraindications:

Hypersensitivity, bleeding of unknown etiology in the genital area, malignant tumors of the uterus or mammary glands, caused by estrogen deficiency.

With care apply at the first sign of a migraine, frequent unusually severe headaches, the first signs of phlebitis or thromboembolic phenomena of nature, signs of cholestatic jaundice, a sharp rise in blood pressure, severe visual impairment.

Application of pregnancy and breastfeeding:

Not recommended during pregnancy.

During breastfeeding - with caution, in much reduced doses, since estriol partially penetrates into breast milk.

Side effect:

vaginal irritation accompanied by itching, burning and redness.

At the beginning of treatment - spotting from the vagina, pain and tension of the mammary glands, hypersecretion of cervical mucus, whites, fluid retention and the associated temporary weight gain, nausea and other mild gastrointestinal disorders, rarely - migrenepodobnaya headache, very rarely - a feeling of heaviness in the legs, leg cramps.

Drug Interactions:

Simultaneous treatment with barbiturates, anticonvulsants (eg hydantoins), certain antibiotics (such as cephalosporins, neomycin) may reduce effectiveness.

Dosage and administration:

Vaginally, unless indicated otherwise, 1 supp. / Day.

Precautionary measures:

Drug treatment should be carried out only under constant medical supervision to conduct gynecological examinations (especially during long and repeated bleeding from the vagina).

In identifying vaginal infection it is necessary to simultaneous treatment.