Expiration date: 05/2025
Composition and form of issue:
Hiporhamin pills
Sublingual tablets 1 table.
dry purified extract of sea buckthorn leaves (Hippophae rhamnoides L.) of the family (Elaeagnaceae) 0, 02 g
excipients: refined sugar cocoa powder, vanillin, sodium carboxymethylcellulose calcium stearinovokisly up to receive the tablets of 0, 6 g
in a contour acheikova packing 10, 20 or 30 PCs or in the banks dark glasses to 25 PCs. in cardboard pack 1 pack or Bank.
Hiporhamin lyophilized for solutions of 0, 02 g
Lyophilisate for preparation of solution for inhalation is 1 FL.
dry sterile purified extract from the leaves of sea buckthorn (Hippophae rhamnoides L.) of the family suckers (Elaeagnaceae) 0, 02 g
in vials.
Hiporhamin ointment 0, 5%
Ointment 100 g
dry purified extract of sea buckthorn leaves (Hippophae rhamnoides L.) of the family (Elaeagnaceae), 0, 5 g
excipients: vinylin vaseline twin-80 medical emulsifier ?1 eucalyptus oil nipagin purified water - up to 100 g
the aluminum tubes or jars of dark glass 20 g in a pack a cardboard 1 tube or Bank.
Suppositories rectal with Hiporhamin 0, 05 g
Suppositories for rectal use 1 soup.
dry purified extract of sea buckthorn leaves (Hippophae rhamnoides L.) of the family (Elaeagnaceae) 0, 05 g
the basis for obtaining suppositories (solid fat type A) - sufficient to obtain a suppository weight of 2, 2-2, 6 g
in a contour cell package.
Vaginal suppositories with Hiporhamin 0, 05 g
Vaginal suppositories 1 soup.
dry purified extract of sea buckthorn leaves (Hippophae rhamnoides L.) of the family (Elaeagnaceae) 0, 05 g
vaseline oil is the basis for the production of suppositories (solid fat) — a sufficient number to obtain the suppository mass of 2, 2-2, 6 g
in a contour cell package.
Description of dosage form:
Sublingual tablets-biconvex tablets, with risk, from light gray or light gray with a pinkish tinge to light brown with darker or lighter inclusions.
Ointment-white with a pale cream tint.
Suppositories - from light brown with a yellowish-grayish tinge to brown.
Characteristic:
Polyphenolic complex of galloellagotanins, biologically active components of which are hydrolyzable tannins having common structural elements.
Description of pharmacological action:
It is active against various strains of influenza a and B virus, adenoviruses, paramixoviruses, herpes simplex virus, herpes zoster, cytomegalovirus, respiratory syncytial virus, immunodeficiency virus (HIV infection). The inhibitory effect on virus reproduction occurs in the early stages of virus replication. The basis of the mechanism of action of Hiporhamin lies the inhibitory effect on viral neuraminidase. Induces the production of interferon in blood cells in experiments in vitro and increases the content of interferon in the blood of patients.
In experiments in vitro has a moderate antimicrobial effect against gram-positive and gram-negative bacteria, tuberculous mycobacteria, fungi of the genus Candida, some mycelial fungi.
Hiporhamin low toxicity. Does not have allergenic, mutagenic, teratogenic and carcinogenic properties, does not affect the immune status of the body.
Indications:
- influenza (A and B) parainfluenza, SARS (respiratory syncytial, adenovirus, etc.) angina and rhinitis (against SARS)
- herpes simplex extragenital and genital localization (acute and recurrent)
- herpes zoster, chicken pox
- infections caused by drug-sensitive viruses, including CMV infection (treatment and prevention).
Contraindications:
Hypersensitivity.
Side effect:
It is possible to increase blood clotting (with long - term use in doses exceeding the recommended).
Dosage and administration:
The drug should be prescribed in the early stages of the disease. The most pronounced therapeutic effect is achieved when the combination dosage forms of Hiporhamin resorptive and local action.
Hiporhamin pills
Sublingual. The tablets are kept under the tongue in the mouth until complete resorption.
In influenza, adenovirus, respiratory syncytial and other viral infections of the upper respiratory tract: adults - 1 table. 4-6 times a day, children over 12 years-1 table. 3-4 times a day, 3-12 years-1/2-1 table. 2-4 times a day. Children under 3 years sublingual tablets are not prescribed.
The duration of treatment for influenza at least 3 days, with parainfluenza, respiratory syncytial virus, adenovirus, mixed infections and other ARVI-at least 5 days.
To prevent the development of viral complications in immunosuppressive therapy and in postoperative patients: 1 table. 3 times a day for 5-7 days.
In chickenpox, shingles, herpes and CMV infection, and other viral lesions of the skin and mucous membranes: adults and children over 12 years — 1 table. 4-6 times a day, children 6-12 years-1 table. 3-4 times a day, 3-6 years-1/2 table. 2-4 times a day.
Hiporhamin lyophilized for solutions of 0, 02 g
The drug is used as an aqueous solution prepared ex tempore by adding a bottle of sterile distilled water in a volume of 10 ml (to obtain 0, 2% solution) or 20 ml (to obtain 0, 1% solution).
Inhalation, using a variety of devices (U-1, ultrasound-70, AI-1, etc.).
In influenza, adenovirus, respiratory syncytial and other viral infections of the upper respiratory tract: adults (0, 2% solution) — up to 10 ml for inhalation to children (0, 1% solution) older — up to 10 ml for inhalation, younger-up to 5 ml for inhalation.
When rhinitis-buried in each nasal passage of adults 4-6 drops of 0, 2% solution 3-4 times a day, children-2-4 drops of 0, 1% solution 2-3 times a day.
Hiporhamin ointment 0, 5%
Outwardly. In chickenpox, shingles, herpes and CMV infection, other viral lesions of the skin and mucous membranes: applied to lesions 4-6 times a day.
Suppositories rectal with Hiporhamin 0, 05 g
Per rectum. In influenza, adenovirus, respiratory syncytial and other viral infections of the upper respiratory tract: adults-0, 05 g 1-2 times a day, depending on the severity of the process (the presence of pneumonia, hyperthermia).
The duration of treatment for influenza at least 3 days, with parainfluenza, respiratory syncytial virus, adenovirus, mixed infections and other ARVI-at least 5 days.
To prevent the development of viral complications in immunosuppressive therapy and in postoperative patients: adults — 0, 05 g 2 times a day for 5-7 days.
Vaginal suppositories with Hiporhamin 0, 05 g
Intravaginal. In genital herpes, additional adults-0, 05 g 1-2 times a day. The duration of application depends on the severity of the process and is in mild forms of the disease 3-10 days. In severe and recurrent forms of the disease - at least 2-3 weeks. It is advisable to conduct repeated courses of treatment.
In chickenpox, shingles, herpes virus and CMV infection, and other viral lesions of the skin and mucous membranes, sublingual tablets of 0, 02, ointment 0, 5%, suppositories rectal and vaginal 0, 05 (for adults) are used.
For individual prevention in the period of outbreak of influenza using sublingually tablets, rectal suppositories and Hiporhamin lyophilized in the form of nasal instillation according to the schemes described above.
Overdose:
When using the drug in the form of aqueous solutions in concentrations above 0, 2% possible irritation of the nasal mucosa.
When using other dosage forms of intoxication was not observed.
Special instruction:
The tablet contains 0, 5299 g of sugar. Patients with diabetes should consult a doctor before starting treatment.
