Expiration date: 06/2025

Structure and Composition: 

Vaginal Tablets. 1 tablet contains itraconazole 200 mg

Excipients: lactose (milk sugar), sodium lauryl sulfate, potato starch povidone (polyvinylpyrrolidone) Magnesium stearate Talc

in blisters or in plastic cans and dark glasses to 1 or 10 pcs. In the paper cartons 1 package or a bank.

Description pharmaceutical form:

Tablets white or nearly white in the form of a ring.

Pharmacokinetics:

With intravaginal administration to create effective local concentration of itraconazole. Systemic absorption is minimal.

Description of the pharmacological actions:

Itraconazole - triazole derivative. Synthetic broad antifungal spectrum. It violates the synthesis of ergosterol, which is an important component of the fungal cell membrane. It is active against infections caused by the yeast-like fungi and yeasts: Candida spp, including C. albicans, C. glabrata and C. Krusei etc...

Indications:

Local treatment of vulvovaginal candidiasis (including recurrent).

Contraindications:

• Hypersensitivity to itraconazole and other ingredients
  
• pregnancy (I term).
  

Application of pregnancy and breastfeeding:

Contraindicated in I trimester of pregnancy, with caution - in the II and III trimester (the drug can be used only if the expected benefit to the woman outweighs the potential risk to the fetus) lactation (if necessary appointment of itraconazole should stop breastfeeding).

Side effect:

Rarely - itching, burning sensation in the vagina, skin rash in the area of ??the external genitalia that do not require discontinuation of therapy.

Dosage and administration:

Vaginally. Vaginal tablets inserted into the vagina once in the evening before going to bed, in the "supine" when slightly bent legs. The course of treatment - 7-14 days. Repeated treatment is possible after consultation with the doctor.

Overdose:

Use of the drug in high doses does not cause any reactions and conditions, life-threatening.

Treatment: In case of unintended use of the drug (oral) is necessary to gastric lavage and activated charcoal to appoint inside. No specific antidote.

Special instructions:

simultaneous treatment of sexual partners is necessary to prevent reinfection.

During treatment advised to refrain from sexual intercourse.

should practice good hygiene to prevent reinfection.

If clinical signs of infection persist after treatment, there should be repeated microbiological examination to confirm the diagnosis.

If you have an allergic reaction, treatment should be discontinued. If necessary, the preparation may be removed by washing with boiled water vagina.

The drug does not affect the performance of potentially hazardous activities that require concentration and rapid psychomotor reactions (driving, etc.).