Expiration date: 10/2025

Composition

100 g gel contains active substance: Ketoprofen 2.5g or 5 g

Pharmacotherapeutic group

Nonsteroidal anti-inflammatory drug (NSAID)

Pharmacological action

It has a local anti-inflammatory, anti-exudative and analgesic effect. By inhibiting cyclooxygenase I and type II, inhibits the synthesis of prostaglandins. 

It has antibacterial activity, stabilizes lysosomal membranes and delays the release of enzymes that contribute to tissue destruction in chronic inflammation. 

Ketoprofen, penetrating through the skin, reaches the center of inflammation, thus providing the possibility of local treatment of lesions (joints, tendons, ligaments and muscles), accompanied by pain. When the joint syndrome causes a weakening of pain in the joints at rest and when moving, reducing morning stiffness and swelling of the joints.

Indications for use

• Acute and chronic inflammatory diseases of the musculoskeletal system (joint syndrome in acute gout, rheumatoid arthritis, psoriatic arthritis, ankylosing spondyloarthritis, osteoarthritis, osteochondrosis with root syndrome, radiculitis, inflammatory ligaments and tendons, bursitis, sciatica, lumbago). 
  
• Muscle pain of rheumatic and non-rheumatic origin. 
  
• Post-traumatic inflammation of soft tissues and musculoskeletal system (injuries and ruptures of ligaments, injuries). 
  

The drug is intended for symptomatic therapy, reduce pain and inflammation at the time of use, the progression of the disease does not affect.

Contraindications

• individual hypersensitivity to Ketoprofen or other ingredients of the drug, acetylsalicylic acid or other NSAIDs (indicate a history of bronchospasm, urticaria or rhinitis caused by acetylsalicylic acid); tiaprofenic acid and fenofibrate; 
  
• full or partial combination of bronchial asthma, recurrent polyposis of the nose or paranasal sinuses and intolerance of acetylsalicylic acid and other NSAIDs (including history); 
  
• increased sensitivity of the skin to the effects of solar radiation (photosensitization) in the anamnesis; 
  
• skin Allergy in the anamnesis on a sunscreen or perfumes; 
  
• exposure to the sun on the treated areas, including the Solarium during the course of the drug and 2 weeks after. 
  
• wet dermatoses, eczema, infected abrasions, wounds (at the site of application of the gel); 
  
• children under 12 years of age (efficacy and safety have not been studied); 
  
• pregnancy (III trimester) and breastfeeding.
  

Method of application and doses

For external use. A strip of gel 5-10 cm long is applied with a thin layer to the affected area or skin over the inflammation center 2 times a day and lightly rubbed. The amount of gel applied depends on the size of the treated area.

Form release

Gel for external use 2.5% or 5%. 30, 50 or 100 g is placed in aluminum tubes. Each tube together with the instruction on application place in cardboard packing (pack).